How the First Nine Months Shape the Rest of Your Life

Time Magazine highlighted the pioneering work of David Barker, professor of medicine at OHSU in an October 4, 2010 article by Annie Murphy Paul.,8599,2020815,00.html

Professor David Barker honored by March of Dimes

Researcher Who Linked Fetal Nutrition to Adult Disease Honored By March of Dimes

30th Anniversary of Agnes Higgins Award Recognizes David Barker, MD, PhD, FRS 

Children Born to Mothers With Preeclampsia Are at Increased Risk for Stroke Later in Life

Study suggests preeclampsia damages blood vessels in the baby's brain.

It’s been shown that women who develop preeclampsia are at increased risk of cardiovascular disease later in life, and that their babies have higher blood pressure during childhood. What hasn’t been known are the long-term health risks for these children. A recent study by Oregon Health & Science University researchers found these children are at increased risk for stroke later in life. 

Preeclampsia in pregnancy is characterized by high blood pressure and protein in the urine. Without proper care, the condition can lead to serious complications, including death, for both mother and baby.  


Kent Thornburg, Ph.D., and David Barker, M.D., Ph.D., both of the OHSU Heart Research Center, collaborated with Eero Kajantie, M.D., at the National Public Health Institute in Finland and reviewed the maternity records of 6,410 singleton babies born in Helsinki between 1934 and 1944. They found 284 of the pregnancies were complicated by preeclampsia and another 1,592 were complicated by gestational hypertension. 


Dr. Jack Kron exemplifies the Heart Research Center’s focus on translating research into patient care.
Dr. Kron, professor of Medicine, director of the Electrophysiology Laboratory, and a member of the Heart Research Center, specializes in electrophysiology and clinical arrhythmia treatment (irregular heartbeat).
Millions of people experience irregular heartbeat during their lives. For most of us, these experiences are harmless and not indicative of heart disease. 
For some of us, however, such rhythm disturbances can be serious and sometimes fatal. And at times, due to underlying heart disease, the possibility of arrhythmia and associated risks is increased.

OHSU Researchers Identify Master Switch That Regulates Blood Pressure

Improving Communication Among Researchers

Thornburg with model of human heart

Several years ago, Dr. Kent Thornburg crossed paths with the OHSU chief of cardiac surgery who was on his way to an operation for a child with outflow obstruction to the right ventricle. (The right ventricle had to work terribly hard to pump blood through that vessel.) When the chief wondered out loud what happened to the heart muscle when this happens, Thornburg knew there was a problem with his organization. “There are people in my lab who are working on that problem,” he told his colleague. The chief had no idea.